PeptideDB

Cognitivo

Os peptídeos cognitivos são pesquisados por efeitos em memória, foco, neuroproteção e neuroplasticidade. Muitos atuam na sinalização neurotrófica ou sistemas de neurotransmissores e são estudados em modelos de declínio cognitivo.

Adalank

Emerging research

N-Acetyl Selank Amidate | Enhanced Tuftsin Analog

Enhanced derivative of Selank with improved stability, blood-brain barrier penetration, and extended half-life compared to parent compound. Parent compound Selank approved in Russia since early 2000s.

CognitivoLongevidade

Adamax

Emerging research

Next-Generation Semax Derivative | Nootropic Neuropeptide

Synthetic nootropic peptide with N-terminal acetylation and C-terminal adamantane modification for superior stability and blood-brain barrier penetration, researched for cognitive enhancement,

CognitivoLongevidade

Ara 290

Extensively studied

Tissue-Protective Peptide | Innate Repair Receptor Agonist

Ara 290 is an engineered 11-amino acid peptide activating the Innate Repair Receptor (IRR) to provide tissue-protective effects without red blood cell stimulation. Has FDA Orphan Drug status.

Recuperação e CicatrizaçãoCognitivo

Cerebrolysin

Well studied

Neuropeptide Preparation | Neurological Recovery

Standardized neuropeptide preparation containing bioactive peptides and amino acids exhibiting neurotrophic and neuroprotective properties for stroke recovery, traumatic brain injury, and cognitive

CognitivoLongevidade

Cortagen

Moderate research

AEDP | Brain Cortex Bioregulator Peptide

Cortagen is a Khavinson bioregulator tetrapeptide (AEDP) with primary effects on the brain and central nervous system. Developed at Russia's St.

CognitivoLongevidade

Cyclic Glycine-Proline

Moderate research

IGF-1 Bioavailability Regulator & Neuroprotective Peptide

Endogenous cyclic dipeptide found in plasma, breast milk, and cerebrospinal fluid. Functions as metabolite of IGF-1, regulating its bioavailability through competitive binding to IGFBP-3.

CognitivoLongevidade

Dihexa

Emerging research

Synaptogenic Peptide | Cognitive Enhancement

Dihexa is a synthetic oligopeptide derived from angiotensin IV that potently enhances cognitive function by promoting synaptogenesis.

CognitivoLongevidade

DNSP-11

Limited research

GDNF-Derived Peptide | Dopaminergic Neuroprotection

DNSP-11 is an 11-amino acid peptide derived from the pro-domain of glial cell line-derived neurotrophic factor (GDNF).

Cognitivo

DSIP

Emerging research

Delta Sleep-Inducing Peptide | Sleep & Stress Modulator

DSIP is a naturally occurring nonapeptide discovered in 1974 in rabbit brain. Originally isolated for sleep-promoting properties, it has diverse neuromodulatory effects including stress reduction,

SonoCognitivo

FGL

Limited research

NCAM-Derived Peptide | Synaptic Plasticity & Neuroprotection

FGL is a synthetic peptide derived from the second fibronectin type III module of neural cell adhesion molecule (NCAM).

Cognitivo

Humanin

Moderate research

Mitochondria-Derived Peptide | HN

Humanin was the first mitochondria-derived peptide (MDP) discovered, originally cloned from the occipital lobe of an Alzheimer's patient.

LongevidadeCognitivo

IllumiNeuro Protocol

Limited research

Four-Peptide Cognitive Enhancement Blend

IllumiNeuro is a cognitive enhancement peptide blend combining four nootropic peptides: PE-22-28 (neuritogenic), Pinealon (pineal bioregulator), NA-Semax Amidate (neuroprotective/cognitive), and

Cognitivo

NA Semax Amidate

Well studied

Enhanced Nootropic Peptide | Cognitive Enhancement & Neuroprotection

Enhanced and stabilized version of Russian nootropic Semax with superior stability, extended half-life, and enhanced bioavailability through acetylation and amidation modifications.

CognitivoLongevidade

NA-Selank Amidate

Moderate research

N-Acetyl Selank Amidate | Enhanced Anxiolytic Nootropic

NA-Selank Amidate is an enhanced version of Selank, the anxiolytic nootropic peptide developed at Russia's Institute of Molecular Genetics.

CognitivoLongevidadeImunológico

Oxytocin

FDA-approved

Neurohypophysial Peptide | Social Bonding & Reproductive Hormone

Nine-amino-acid peptide hormone produced in hypothalamus, released by posterior pituitary. Functions in social bonding, trust, empathy, reproduction, childbirth, lactation.

HormonalCognitivo

P21

Emerging research

P021 | CNTF-Derived Neurogenic Peptide

P21 is a nootropic peptide derived from ciliary neurotrophic factor (CNTF) that enhances neurogenesis and cognitive function.

CognitivoLongevidade

PE-22-28

Emerging research

TREK-1 Channel Blocker | Shortened Spadin Analog

Synthetic heptapeptide derived from Spadin positions 22-28, functioning as potent TREK-1 antagonist with enhanced selectivity and duration versus parent compound.

CognitivoLongevidade

Pinealon

Well studied

Synthetic Tripeptide | Neuroprotection & Cognitive Enhancement

Developed in Russia, Pinealon demonstrates unique DNA-interaction for neuroprotection and cognitive enhancement.

CognitivoSonoLongevidade

Selank

Well studied

Anxiolytic & Nootropic Peptide | Tuftsin Analog

Selank is a synthetic heptapeptide analog of the naturally occurring immune peptide tuftsin, developed by the Russian Academy of Sciences.

CognitivoLongevidadeImunológico

Semax

Well studied

Synthetic ACTH Analog | Nootropic & Neuroprotective Peptide

Semax is a synthetic heptapeptide derived from adrenocorticotropic hormone (ACTH) fragment 4-10, originally developed in Russia for stroke recovery.

CognitivoLongevidade

VIP

Extensively studied

Vasoactive Intestinal Peptide | Neuropeptide

Vasoactive Intestinal Peptide (VIP) is a 28-amino acid neuropeptide belonging to the glucagon/secretin superfamily. It is produced in many tissues including the gut, pancreas, and brain.

ImunológicoCognitivo